Differential Expression of Ldh Isozymes in the Testis of the Indian Pygmy Field Mouse, Mus Terricolor

Lactate dehydrogenase (LDH) isozyme study in the liver, kidney and testes of Mus terricolor, an indigenous species of India, revealed the presence of a slow migrating variant of LDH isozyme, LDH-C4 along with other five usual LDH isozymes present in other tissues. The synthesis of LDH-C4 is controlled by a separate locus Ldh c. The results have shown differential expression of LDH-C4 and LDH-A4 in the testes of matured (adult) and immature(sub adult) male mice. The results indicated that the C4 expression was very high compared to a low expression of A4 in the testes of matured males while a reverse situation was noticed in the testes of immature males. The differential expression of LDHC4 in testis appears to have some correlation with the sexual maturity of the mouse.